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117 MakiuchiA.YamauraK.MizunoS.MatsumotoK.NakamuraT.AmanoJ.et al (2007)

While not everyone who has tried these medications continues using them, the fact that nearly 20% of the population has taken the time to get a prescription and purchase GLP-1 medications indicates just how popular they have become in a short time

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Severe B3 deficiency (pellagra) causes gastrointestinal, dermatological, and neuropsychiatric symptoms including depression, insomnia, and hallucinations that can either mimic or intensify withdrawal symptoms

That caveat matters, and we'll come back to it