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prescribers should consult current NICE guidance and MHRA licensing.) According to NICE NG28 , GLP-1 receptor agonists are recommended for type 2 diabetes when metformin and other oral medications have not achieved adequate glycaemic control, or as an alternative to insulin therapy in appropriate patients

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They go best with diet and exercise changes, and when used in moderation

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In the case of GLP-1s, this is largely due to a lack of knowledge about their effects