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More energy is needed to overcome the stronger electrostatic forces of attraction between the metal ions and sea of delocalised electrons , resulting in higher melting point

this impacts how often it needs to be taken throughout the day to ensure the drug remains at levels in the blood

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Whilst muscle pain is not listed amongst the common adverse effects of Ozempic (semaglutide) in UK regulatory documentation, some patients do report musculoskeletal discomfort during treatment

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