Mulherin DM, Thurnham DI, Situnayake RD
Note: Under no circumstances should people suddenly stop taking antidiabetic drugs, especially insulin
Given the popularity of Ozempic, this approach is understandable
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Gut elimination of uric acid, which couples transport into the small intestinal lumen and colonic bacterial urate oxidation by uricase, normally removes ~200 mg of uric acid daily in humans ( Figure 1 - 3A ), but this elimination pathway has limited potential for adaptive increases in capacity beyond ~100 mg more daily
The medication can significantly affect blood sugar, so insulin or other diabetes medications often need reduction to prevent low blood sugar