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Indeed, the mBDNF isoform is technically difficult to measure, as antibodies directed against mature BDNF also recognise pro-BDNF, since the pro-BDNF isoform contains the mature BDNF sequence within its structure 31,32

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Slow dose titration and adequate meal planning minimize this risk

Additionally, TBE001-A-S033 demonstrated a clear advantage over insulin icodec in reducing HbA1c levels at both dosages (Fig

Our results indicate that no significant differences were suggested for PE (HR = 1.20, 95% CI = 0.881.64), stroke (HR = 1.14, 95% CI = 0.881.49), heart failure (HR = 1.16, 95% CI = 0.981.38), or MI (HR = 1.27, 95% CI = 0.901.78) (Fig 6)