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Similar results have been obtained in other studies (Lee et al, 2003)

For example, liraglutide, a GLP-1 receptor agonist, improved cognitive function in n = 19 patients with major depressive disorder (MDD) or bipolar disorder in a pilot randomised controlled trial (RCT) [16], whilst a systematic review and meta-analysis reported a pooled reduction in depressive symptoms with GLP-1 receptor agonists compared to other antidiabetic therapies [17]

By acting on central amylin receptors (particularly in the area postrema and hindbrain), cagrilintide reduces appetite and energy intake [3] [10]