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Phosphorylation-dependent interaction between the splicing factors SAP155 and NIPP1

Gastroenterol ., 45 (10), 841843

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A key event in this activation is the unwinding of the U4/U6 snRNA duplex, followed by the release of the U4 snRNP and B-specific proteins, and the recruitment of various protein complexes such as the NTC (Nineteen), NTR (Nineteen-related), RES (retention and splicing), and IBC (intron-binding) 12,13,14,15,16