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doi: 10.1016/j.jaad.2014.03.019 140 MashalyMEKotbHMAbdinAAHedyaSE

The method for synthesizing Cagrilintide as claimed in claim 1, wherein the specific step of cyclization in step four comprises: dissolving the linear peptide crude product in acetonitrile water according to the dose that 1g of the linear peptide crude product is dissolved in 100mL of 50% acetonitrile water solution, adding purified water to dilute the linear peptide crude product to 1g/L after the linear peptide is dissolved

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Magnesium Chloride: Olympias magnesium chloride solution is formulated for IV infusion only

This suggests that FMD is a viable strategy for decreasing plasma TMAO levels by restricting the intake of calories and animal-derived proteins [53]

1j and Extended Data Fig