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It should include the extent, severity and duration of symptoms, frequency of bowel movements, associated symptoms (e.g., constipation, fecal incontinence), daily dietary habits and details of bowel movements (e.g., time spent during each bowel movement and concomitant cell phone use).3 Advertisement Regarding bowel habits, some patients experience lifelong constipation or diarrhea

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The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation