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Tom-Castro XM, Rodriguez-Arrastia M, Cardona D, Rueda-Ruzafa L, Molina-Torres G, Roman P

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doi: 10.3390/antiox11051034 Summary Keywords osteoarthritis, ferroptosis, metabolic reprogramming, immunometabolic crosstalk, iron homeostasis, lipid peroxidation, inflammatory microenvironment Citation Xia S, Li L, Shi Z, Sun N and He Y (2025) Ferroptosis in osteoarthritis: metabolic reprogramming, immunometabolic crosstalk, and targeted intervention strategies

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Lin Q, Xue Y, Zou H, Ruan Z, Ung COL, Hu H

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Scientific Information L-Carnitine Molecular Formula: C 7 H 15 NO 3 Molecular Weight: 161.20 g/mol CAS Number: 541-15-1 Structure: (R)-3-Hydroxy-4-(trimethylazaniumyl)butanoate Classification: Quaternary ammonium amino acid derivative L-Arginine Molecular Formula: C 6 H 14 N 4 O 2 Molecular Weight: 174.20 g/mol CAS Number: 74-79-3 Structure: (S)-2-Amino-5-guanidinopentanoic acid Classification: Basic cationic alpha-amino acid L-Methionine Molecular Formula: C 5 H 11 NO 2 S Molecular Weight: 149.21 g/mol CAS Number: 63-68-3 Structure: (S)-2-Amino-4-(methylsulfanyl)butanoic acid Classification: Sulfur-containing essential amino acid myo-Inositol Molecular Formula: C 6 H 12 O 6 Molecular Weight: 180.16 g/mol CAS Number: 87-89-8 Structure: cis-1,2,3,5-trans-4,6-Cyclohexanehexol Classification: Cyclohexane polyol Choline Listed Concentration: 50 mg/mL Structure: 2-Hydroxyethyl(trimethyl)azanium Classification: Quaternary ammonium compound Pyridoxine (Vitamin B6) Molecular Formula: C 8 H 11 NO 3 Molecular Weight: 169.18 g/mol CAS Number: 65-23-6 Structure: 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol Classification: Pyridine-derivative water-soluble vitamin B6 vitamer Dexpanthenol (Vitamin B5) Molecular Formula: C 9 H 19 NO 4 Molecular Weight: 205.25 g/mol CAS Number: 81-13-0 Structure: (2R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide Classification: Alcohol analog of pantothenic acid Vitamin B12 (Cyanocobalamin) Listed Form: Cyanocobalamin Listed Concentration: 1 mg/mL Classification: Cobalamin-family vitamin B12 compound Key Features Concentration: 216 mg/mL Fill volume: 10 mL Total active content per vial: 2,160 mg Includes L-Carnitine, L-Arginine, L-Methionine, myo-Inositol, Choline, B6, B5, and B12 Sterile, sealed research vial with tamper-evident flip cap Lot and batch labeling for traceability Specifications Type: Sterile aqueous solution Appearance: Red liquid Concentration: 216 mg/mL Volume: 10 mL Total active content: 2,160 mg Documentation: Lot and batch labeling for traceability Packaging: Sterile glass vial, flip-off cap Storage (unopened): Cool, dry, protected from light After opening: Follow approved internal laboratory SOPs

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Ingredients 250 ml schisandra berries 500 ml filtered water 200 g organic honey or agave syrup How to make schisandra berry syrup Blend the schisandra berries to maximise the surface area

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