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GLP-1 receptor agonists (GLP-1RAs) increase GLP-1 levels by 10 times or more and exert several pharmacological actions, including appetite-suppressant effects and delayed gastric emptying

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A history of pancreatitis Pancreatitis (inflammation of the pancreas) has been reported in people on GLP-1 medications, though its uncommon and the absolute risk increase is small

doi: 10.1016/j.bbrc.2006.05.063 39 RashighiMHarrisJE

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By understanding its relationship with other IGF-1 isoforms like MGF, its systemic effects, and its regenerative potential, researchers and practitioners can better appreciate its role in performance, recovery, and longevity optimization.