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Alteration of indigenous gut microbiota is a risk factor for gallstone formation [49]

For others, the stress of adhering to weight loss goals may cause guilt or shame if results arent as hoped

For instance, EVs generated from breast cancer cells can transcytose into the intact blood-brain barrier (143), and were used therapeutically to target the brain (139)

Insulin resistance, common in obesity, stimulates ovarian and adrenal androgen production while reducing sex hormone-binding globulin (SHBG) levels, resulting in increased bioavailable testosterone

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