Its cysteinyl thiol is the key reactive center, supporting reduction reactions, electrophile conjugation, and thiol-disulfide exchange
Kodama, T
NAC may be useful when: Cysteine availability may be limiting The goal is to support internal glutathione synthesis Direct glutathione is poorly tolerated A clinician has identified a relevant medical or nutritional reason NAC does not guarantee that glutathione production will increase adequately
doi:10.1023/b:mebr.0000043979.58915.41[PubMed] 82
Hoffman Y, Aflalo C, Zarka A, Gutman J, James TY, Boussiba S
doi: 10.3389/fpls.2024.1373801 Received 20 January 2024 Accepted 23 February 2024 Published 12 March 2024 Volume 15 - 2024 Edited by Ahmed Abdelkhalek, City of Scientific Research and Technological Applications, Egypt Reviewed by Nuria Montes, Hospital Universitario de La Princesa, Spain Updates Copyright 2024 Kozie, Otulak-Kozie and Rusin