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This damage is characterized by disorganization, hypertrophy, and proliferation of vascular smooth muscle cells, as well as the destruction of endothelial cells and thickening of the middle layer of the endothelium, all of which contribute to an increased risk of atherosclerosis

Results Administration of GLP-1RAs reduced nicotine self-administration and nicotine-seeking behaviour in animal models that, in some cases, is sustained beyond exposure to the agent