Li et al., 2025
3.3 Accelerating the recovery of exercise-induced fatigue 3.3.1 Role of UA in alleviating inflammatory responses The overtraining-cytokine hypothesis proposes that prolonged stress, insufficient recovery periods, and disrupted sleep patterns may trigger sustained cytokine release, leading to chronic systemic inflammation, which is hypothesized to underlie the development of chronic fatigue in athletes (50, 51)
A compromised gut barrier is both a cause and a consequence of dysbiosis, and intervening at the level of mucosal integrity, which is precisely what BPC-157 does in animal models, represents a mechanistically coherent approach to gut-mediated systemic aging
Guo H, Wang H, Huo Y-X (2020) Engineering critical enzymes and pathways for improved triterpenoid biosynthesis in yeast
& Dosio, F
Plant Physiol Biochem 48:663672 Chen JH, Jiang HW, Hsieh EJ, Chen HY, Chien CT, Hsieh HL, Lin TP (2012) Drought and salt stress tolerance of an Arabidopsis glutathione S -transferase U17 knockout mutant are attributed to the combined effect of glutathione and abscisic acid