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The SUSTAIN trial program (multiple Lancet and NEJM publications 2017 through 2019) is the clinical reference

By starting small and increasing the dose slowly, these patients can benefit from the medication while minimizing risks

Understanding the difference between microdose exposure and full therapeutic dosing helps clarify why low-dose experiences may not match the outcomes reported in trial data

H., Kang, J

However, if its near the time for your next dose, skip the missed dose and continue with your regular dosing schedule

For many people, losing weight brings improvements to their overall health, energy levels, mobility, and confidence, which are benefits that far outweigh the very small risk of severe reactions