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The commercial describes Hims life-changing weight loss medications as affordable, doctor trusted, and formulated in the USAthough its use of the oblique term formulated, rather than manufactured or made, raises questions about where its active pharmaceutical ingredient, semaglutide, is sourced, particularly because Novo Nordisk has made clear it does not sell its API to anyone else and there is evidence compounders have been sourcing API from uninspected or unregistered foreign facilities

In addition to their antidiabetic effects, GLP-1R agonists have shown substantial benefits in promoting weight loss, largely through appetite suppression and delayed gastric emptying

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