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Saunders takes a similarly cautious strategy with her patients: When our patients are off medication for an extended period, we generally recommend starting back at the lowest dose and titrating up gradually. The more doses a person has missed, the more likely they are to have difficulty tolerating the medication when they restart it, and the more likely they are to have gastrointestinal side effects, Low Wang says
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( E ) Mitochondrial glucose oxidation was calculated in caSMCs treated with MTP siRNA (black bars) or control siRNA (white bars) and pretreated with 100 nM GLP-1(2836) or scrambled control ( n = 3/treatment, each in triplicate)
Bajoria, P
Four patients were noncompliant with the diet
