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In response to ingested meals, GLP-1, an incretin hormone, stimulate glucose-dependent insulin secretion, suppress glucagon, prolong gastric emptying, and promote glucose uptake into muscles and adipose tissues (3)
Seek emergency medical attention immediately if you experience more severe symptoms, such as difficulty breathing, dizziness, or swelling of the face or throat, as these could be signs of a serious allergic reaction (anaphylaxis)
These side effects are generally short-lived and will subside as your body gets used to Wegovy
In the broader obesity studies that made these medicines familiar, semaglutide reached 14.9% mean weight loss at 68 weeks in STEP-1 (n=1,961) and tirzepatide reached 20.9% at 72 weeks on the highest-dose arm in SURMOUNT-1 (n=2,539)
This adjustment period may result in temporary muscular strain, particularly in the lumbar region