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The four hero molecules I have endorsed for inclusion in the Syntha-Pep formulation, GHK-Cu, sh-Oligopeptide-1 (the EGF analog), PDRN, and a multi-molecular-weight HA system, are the four with the strongest peer-reviewed clinical evidence supporting their use specifically in a delivery-enhanced context

injection, add sufficient solute to make an approximately isotonic solution

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Microdermabrasion is not recommended during pregnancy due to increased skin sensitivity and limited safety research

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But the data has gaps and limits