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Recent FDA Guidance on Compounded GLP-1s: In October 2023, the FDA issued warnings about compounded GLP-1 medications, specifically cautioning patients to ensure theyre receiving semaglutide (the actual FDA-approved ingredient) rather than semaglutide salts, which have different properties

All research involving this compound should be conducted under appropriate institutional biosafety regulations

it is a subcutaneous injection, meaning it needs to be injected just under the skin

[10] Gastrointestinal disturbances-including nausea, loose stools, and a transient fishy body-odor attributable to trimethylamine production from excessive carnitine and choline metabolism-occur in a minority of recipients and are usually self-limiting within 24 to 48 hours after injection

PD (Blood Glucose Lowering) OGTT Glucose AUC 0-2h on Day 23 was significantly decreased with HS-20094 compared with placebo, in a dose-dependent manner

However, insurance plans typically do not cover drugs for their off-label uses, so the coverage request will likely be denied