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Reduced systemic inflammation may lower the inflammatory tone in the brain

The dose escalation schedule of these medications also plays a role, with gastrointestinal symptoms often more pronounced during dose increases

GLP-1 And GLP-1 Receptor Agonists (GLP-1RA) GLP-1 (Glucagon-like peptide-1) is a peptide hormone encoded by the glucagon-like gene of human islet and secreted by intestinal L cells

RSK2, p90 ribosomal S6 kinase 2

While results have been mixed, this remains an active area of research with promising potential