Additionally, antidepressant use was associated with a 70% higher risk of aspiration pneumonia, cerebral infarction, and fall-related incidents, a 60% increase in serotonin syndrome, a 47% increase in gastrointestinal bleeding, an 80% higher risk of obesity, and a fivefold increase in suicidal ideation
That timeframe refers to pharmacologic clearance, while noticeable effects such as appetite suppression and blood sugar control typically fade earlier as blood levels decline
Peralta-Reich suggests that close monitoring is important for older patients especially if they have other health conditions, such as high blood pressure, diabetes, and hormonal deficiencies since dosage may change over the course of treatment
Also if you have hyperthyroidism, you must limit your iodine intake
Another study treated 25 men with type 2 diabetes and hypogonadism with either a GLP-1 drug or TRT, and found that in 24 weeks both groups had higher testosterone levels
Lab testing is essential to personalize protocols and avoid imbalances