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In another randomized controlled trial of 79 women with episodic migraines without aura, supplementation with 300 mg lipoic acid twice daily was found to significantly reduce mood symptoms of depression, anxiety, and stress (assessed by DASS-21, a standardized scoring system) compared with placebo (Rezaei Kelishadi 2021)

DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cells