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These microbial changes correlate with higher lipopolysaccharide (LPS) and lower superoxide dismutase-1 levels (59, 60), which can lead to microbial translocation, systemic inflammation, and increased permeability of both the intestinal and blood-brain barriers (BBB), creating a vicious cycle (6165)

PMID: 31955824 Anal Chem Viability-Informed Single-Cell Mass Spectrometry for More Comprehensive Metabolic Analysis

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In this regard, the implementation of in vivo animal studies and clinical trials to evaluate the suicidal death of erythrocytes in tissue and organ contexts represents a key objective to be pursued

2:43-49 (2012) Tan JP, Jahim JM, Wu TY, Harun S, Mumtaz T