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Description

VEGF-mediated angiogenesis restores capillary supply to crushed or transected muscle, which is rate-limiting for repair in larger soft-tissue injuries

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However, baseline liver function tests (LFTs)including alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and bilirubinmay provide a useful reference point should concerns arise during treatment

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The initial dose for many patients is 2.5 mg once weekly, which is often increased over time based on tolerance and treatment goals

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