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The only time youd know for sure if the biotin is an issue is if you had no acne to start with, you then took a biotin-only supplement (and changed nothing else , like skincare, stress etc), experienced acne, then when you stopped it cleared

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Peak BAC reduced approximately 2035% and delayed 3045 minutes vs fasting

By day 3-4 of multi-dose use, microbial contamination becomes likely