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Although some damage to proteins, lipids, and mitochondrial DNA occurs, mitochondrial oxidative stress and mitochondrial membrane permeability transition activation are the key events in acetaminophen-induced hepatic cell necrosis [45, 46]

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Euroasian J

IL-1, a cytokine for establishing an in vitro model of OA [83], can induce osteoclast (OC) catabolism by disrupting iron homeostasis by promoting iron influx and increasing matrix metalloproteinase (MMP) expression [84]

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Difficulty Breathing or Swallowing Seek urgent care for trouble breathing, throat tightness, severe wheezing or difficulty swallowing