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At 25 weeks of age, mice were divided into groups receiving daily subcutaneous injections of vehicle, 150 nmol/kg/day salmon calcitonin, or 3 nmol/kg/day Cagrilintide for three weeks

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The work presented here demonstrates for the first time that propionate-stimulated PYY release from primary FFA2 / colonic cultures is also significantly attenuated and that, unlike WT animals, FFA2 / mice do not respond to propionate

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