7 According to a study done by Bernardo Yusta from the University of Toronto in Toronto, Canada and colleagues, treatment of diabetic rats with exendin-4 can significantly reduce biochemical markers of islet endoplasmic reticulum (ER) in beta cells
However, liraglutide did not directly activate Fos expression in the PVH, suggesting that the effects of GLP-1RA on this region may be indirect [95,96]
A diferencia de los GLP1-RA, se ha observado en la evidencia clnica que los IDPP-4 no tienen beneficios cardiovasculares en pacientes con DM2 a pesar de contribuir en el control glucmico, por lo que no cumplen con los nuevos lineamientos en el tratamiento de la DM2, donde se busca reducir la incidencia de complicaciones ms all del control glucmico 58
Cell Metab 17(6):819837 Chang YC, Chan MH, Yang YF, Li CH, Hsiao M (2023) Glucose transporter 4: insulin response mastermind, glycolysis catalyst and treatment direction for cancer progression
Talbot, K
Located near the eye, the superior ophthalmic aneurysm is a rare and challenging condition