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NICE guidance requires at least 5% weight loss after 6 months at maintenance dose for treatment continuation, with maximum recommended duration of 2 years

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[23] Increasing bacterial antibiotic resistance to other commonly used agents, such as trimethoprim/sulfamethoxazole and fluoroquinolones, has led to increased interest in using nitrofurantoin in the contemporary treatment of UTIs

Stress Management : Incorporating mindfulness practices such as meditation or yoga can help manage stress, which in turn supports glutathione levels