How to naturally boost glutathione production depends on these factors, too
Arthur JR (2000) The glutathione peroxidases
Core Studies on Lithium Orotate and GSH Method of treatment of glutathione deficient mammals PatentInactiveUSRE40849E1 A composition comprising N-acetylcysteine, vitamin C, alpha-lipoic acid, silymarin, quercetin, L-glutamine, N-acetyl-d-glucosamine, and probiotics, administered orally, which facilitates gastrointestinal absorption and intracellular uptake to stimulate natural glutathione production, supporting liver function and enzymatic reactions for enhanced glutathione synthesis
References Bahadoran Z, Mirmiran P, Hosseinpanah F, Hedayati M, Hosseinpour-Niazi S, Azizi F
Space these supplements a few hours apart - take NAD with breakfast for lasting energy, and NAC between meals or at bedtime
However, there are no relevant research reports on the mechanism of action of GPX6, which may be related to the oxidative stress response involved in glutathione