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Your GP or endocrinologist should check thyroid function tests (TSH and free T4) before starting weight loss injections and periodically during treatment if you experience symptoms suggesting altered thyroid function or after significant weight change or medication adjustments

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Samples must be collected within two to four hours post-administration to capture measurable concentrations, and immediate processing (centrifugation, plasma separation, freezing at 80C) is essential to prevent ex vivo degradation

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Steve Small: Yeah, well, thats a good question because looking into this, Don, I did find a recent observational study back in November 2025 that looked at over 400,000 patients taking GLP-1 agonists such as semaglutide to see if they had a higher risk of the side effect