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However, there are some theories: Metabolism slows down Feeling tired or lacking in energy leads to a lower activity level Changes in how fat and blood sugar are metabolized by your body Retention of salt and water in tissues leads to weight gain Studies have shown after starting thyroid replacement medication with T4, weight loss can occur

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Impurity Formation in GLP-1 peptide drugs Liraglutide: Liraglutide, a 31-amino acid peptide, is prone to degradation and impurity formation due to its structural features

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