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Fortunately, these complications are relatively rare

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For metabolically healthy individuals without established cardiovascular disease, LDL between 100-130 mg/dL with large, fluffy particles (indicated by low triglycerides and high HDL), low ApoB (below 90 mg/dL), low inflammation (hs-CRP below 1.0 mg/L), and good insulin sensitivity represents a reasonable target that balances cardiovascular protection with avoiding potential downsides of extremely low cholesterol

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