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Consequently, it is of major clinical significance to develop a biomaterial capable of inhibiting ferroptosis and inflammation of degenerative NPCs via reducing excessive ROS accumulation in the microenvironment, thereby restoring NPC viability and ECM homeostasis to promote disc repair, which would perform promising therapeutic efficacy on IDD

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Higher doses raise the risk of stomach symptoms

Outside the cell, copper exists as Cu(II), bound to the STEAP family of metal reductases and reduced to Cu(I), and is taken up into the cell 2

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If denied, BCBS will notify the prescribing healthcare provider