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High concentrations of copper ions can activate autophagy through lysosome-dependent mechanisms [158]

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GLP1 receptor agonists (GLP-1s) are prescription drugs widely used to manage type 2 diabetes, obesity and related chronic conditions such as cardiovascular disease and fatty liver disease

Pharmacokinetics of IGF-1 LR3 The extended half-life of IGF-1 LR3 stems from two features: the N-terminal extension physically blocks IGFBP binding, and reduced clearance via the IGFBP-ALS ternary complex slows hepatic filtration