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Additional limitations were minimal BD data

A water molecule in the close vicinity of Gln390 hydrogen bonded to the hydroxyl group of Ser388 and -amino group of Gly484 has been reported to enhance nucleophilicity of OG atom of Thr391 that appears crucial in autoprocessing (Figure 2

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IV Route: A straight, multi-lane superhighway with no obstacles, where a large transport truck arrives directly at the destination