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For SP1, high expression levels (depicted by yellow points) were predominantly associated with positive SHAP values, whereas low expression (purple points) correlated with negative SHAP values, indicating that SP1 upregulation tends to drive predictions in a positive direction

Tedesco AM, Chiricozzi FR, Clausi S, Lupo M, Molinari M, Leggio MG

Treatment with UA significantly decreased COX-2 expression and subsequent PGE2 production in human primary endometriotic stromal cells, while significantly enhanced the expression of caspase-3

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However, these anticancer agents do not selectively kill senescent cells and have only a narrow safe concentration range

For proteins displayed on the surface, adhesion molecules, which belong to the tetraspanin and integrin families, are the most abundant