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Mechanism of Action In a healthy person, incretins such as GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) are released by the intestines after food is ingested

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Long-term cancer risk in users of GLP-1 agonists in Denmark: a nationwide emulated trial

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Lastly, the high proportion of female participants evaluated in this study is reflective of the natural history of type 2 diabetes in youth [40] and our study results may not be generalisable to males, although there is no evidence to suggest that there are sex differences in glucose production or response to metformin therapy [41]