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On the basis of type of the study, the heterogeneity between the subgroups and within each subgroup was quite high, i.e., 98% among observational studies and 97% among RCT's and a leave-one-out sensitivity analysis showed no significant change in heterogeneity by omitting any study as shown in Fig

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All the animals were kept at room temperature in a 12 h light/dark cycle with free access to food and water

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