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doi: 10.1016/j.jss.2005.05.028 21 LimJSLeeSHYunHLeeDYChoNYooGet al

The early decline in lung function in COPD is correlated with inflammatory changes in the peripheral airways, similar to those that occur in the central airways: exudate of fluid and cells in the airway wall and lumen, goblet and squamous cell metaplasia of the epithelium 43 , edema of the airway mucosa due to inflammation, and excess mucus in the airways due to goblet cell metaplasia

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By inhibiting tyrosinase, the theory is that glutathione reduces melanin production, leading to a lighter skin tone and potentially evening out uneven pigmentation