ccRCC cells are highly sensitive to the consumption of glutamine or cysteine, and the use of erastin, L-buthionine-S, or R-sulfoximine (BSO) can induce cell death by inhibiting GSH synthesis in ccRCC cells in a concentration-dependent manner (87)
doi: 10.1210/endo.133.3.8365359 16 BreljeTCStoutLEBhagrooNVSorensonRL
Can you stay at a low dose instead of going up
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