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It is a multiprotein complex composed of NLRP3 sensor, ASC (apoptosis-associated speck-like protein) and pro-caspase-1

The PTEN-PI3K pathway: of feedbacks and cross-talks

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Moreover, parallel over-expression of AhR and HSP90 as observed by western blot in the present study corroborated the finding as it is suggested that ligand-bound AhR translocates to the nucleus with HSP90 showing its co-localization in the nucleus (Tsuji et al., 2014)

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