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(Figure 3) Some studies have shown that Nox is involved in macrophage phagocytosis and neutrophil bactericidal activity, so Nox has a firmly established importance in immune function ( 2 and H 2 O 2 produced by Noxs in many cell types are essential for normal signal transduction of growth factors and cytokines ( 2 and H 2 O 2 (Morel et al., 2015)