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Phosphoproteomics results were normalized to the total proteomics

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4 In SURMOUNT-1, considerably more tirzepatide than placebo patients experienced GI adverse events, e.g., nausea 30% vs

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When we blocked pyruvate entrance into the TCA cycle or fatty acid import for -Oxidation, we found a significant reduction in intracellular glutamine in IAV infected DC, presumably due to increased glutaminolysis in the absence of other oxidative substrates (S2E Fig)