Neelakantan et al., Biochemical Pharmacology, 2018, gave diet-induced obese mice the compound and reported it significantly reduced body weight and white adipose mass, decreased adipocyte size, with food intake unchanged (PMID 29155147) [3]
Methods Data source and cohort This retrospective cohort study drew on data from the TriNetX Global Collaborative Network, a real-time clinical research platform that aggregates de-identified electronic medical records from more than 135 health-care organizations (HCOs) across the Americas, Europe-Middle East-Africa, and Asia-Pacific regions, encompassing over 130 million patient records
Therefore, some people may take milk thistle supplements instead of glutathione supplements
Not a vague "brightening promise" a documented result with real participants
The most common precursor is N-acetyl cysteine (NAC)
The NHGRI-EBI GWAS Catalog: standards for reusability, sustainability and diversity