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Randomization for the double-blind treatment period Participants who achieved 5.0% weight reduction at the end of the 12-week lead-in period were randomly assigned in a 1:1 ratio to receive either the MTD of tirzepatide (10 or 15 mg) or placebo
The ROS-responsive linker (((ethane-1,2-diylbis(azanediyl))bis(carbonyl))bis(4,1-phenylene))diboronic acid (EBPBA) was synthesized (Supplementary Fig
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Principle The principle of isoelectric focusing involves the establishment of a pH gradient within a gel matrix by incorporating amphoteric electrolytes
Patton JS, Byron PR
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