GLP-1 plays a fundamental role in lowering blood glucose level and controlling body weight through stimulating the islet B cells to secrete insulin, inhibiting gastric emptying and reducing food ingestion (Zietek et al
doi: 10.3389/fphar.2024.1323083 Received 17 October 2023 Accepted 02 January 2024 Published 16 January 2024 Volume 15 - 2024 Edited by Pranav Kumar Prabhakar, Lovely Professional University, India Reviewed by Yong Zhi Lun, Putian University, China Updates Copyright 2024 Buczyska, Kociuszko, Krtowski and Popawska-Kita
Groups were well matched for age, sex, baseline hypertension, heart failure, IHD and CKD
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But targeting GLP-1 receptors in the brain will likely need a small molecule drug