Wegovy is a GLP-1 agonist, a class of obesity drugs promising a sea change in weight loss
Clinical studies show that combining hormone replacement therapy with GLP-1 medications may produce superior results, but individual experiences vary based on numerous factors
Some potential side effects may include: Mild injection site irritation Temporary water retention (rare) Increased hunger (via IGF-1 signaling) Vivid dreams (due to improved deep sleep) Fatigue or lethargy if overdosed Caution: Do not use in individuals with active or suspected cancer, as GH and IGF-1 can stimulate cell growth
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Nausea was also slightly higher
Tirzepatide works to address the timing mismatch by: Slowing gastric emptying which delays how quickly glucose enters the bloodstream Supressing glucagon (a hormone that raises blood glucose) which will help reduce post-meal spikes Reducing appetite which lowers food intake and daily insulin requirements Together, these effects may reduce the mismatch between food absorption and insulin action, making it easier for an automated system to maintain stable glucose levels without manual intervention